Data sources
No third-party aggregators, no training-data guesses. Every verdict traces to the government register that decides it — named, linked, and re-read on a schedule.
Ingredient permissibility, dose ceilings and registration pathway — six markets, each read against its own authority.
TGA · FSANZ
Re-scrubbed monthly — TGA and FSANZ each run on the 1st.
Instrument
The positive list for listed-medicine ingredients — dose limits, use restrictions and label requirements. Re-ingested from the Federal Register of Legislation each time TGA reissues the instrument.
Federal Register of LegislationInstrument
Schedule 29 (permitted supplementary-food substances), Schedule 16 (food additives) and the vitamins & minerals standard — what decides the food-vs-therapeutic boundary.
Food Standards CodeRegister
Every listed and registered therapeutic good, with its declared ingredients — how we show what comparable products on the AU market actually contain.
ARTG public summaryRegister
The Advisory Committee on Novel Foods' published views. A substance ruled novel with no Schedule 25 permission is not permitted in food — the trap that catches ingredients with long traditional use elsewhere.
ACNF record of viewsMedsafe · FSANZ
Reviewed alongside the monthly FSANZ scrub.
Instrument
Medsafe's regulation-3 dose caps and its short prohibited-substance list. A small, specific instrument — deliberately not presented as a broad positive list, because it is not one.
MedsafeInstrument
The same trans-Tasman Code — additive, vitamin and mineral data comes from the identical source as the Australian side, not a separate NZ copy.
Food Standards CodeANVISA
IN 28/2018 and the constituent panel re-scrub monthly, with a dedicated watch for retificações — amendments published in a later gazette issue under the same instrument number. The two open-data registers are a snapshot taken 13 Aug 2026, not yet on a recurring schedule.
Instrument
Annexes I/II — the positive list of constituents authorised for dietary supplements, linked to the exact consolidated PDF our pipeline reads. ANVISA amends it as it authorises new constituents; most recently IN 431/2026 (açaí anthocyanins and polyphenols, two named probiotic strains, and three others) and IN 438/2026 (curcumin and tetrahydrocurcuminoids).
Consolidated instrument (PDF)Live panel
ANVISA's own weekly-updated dashboard of authorised constituents, their function, permitted claims and labelling wording — read from the live panel as an independent cross-check against our PDF parse, not a restatement of it.
ANVISA consultation panelsInstrument
Sanitary requirements for supplements, the separate fitoterápico registration regime, and the regularisation-route framework — four routes (ANVISA authorisation, ANVISA notification, state or municipal communication, exempt). Kept apart so a botanical needing full registro is never reported as notify-and-ship. The companion instrument assigning each category to a route, IN 281/2024, is not ingested: we name it and abstain rather than guess.
RDC 843/2024 (English)Register
ANVISA's open-data register of medicine registrations — whether a substance is registered as a drug in Brazil, which is a different regime from the supplement positive list.
dados.gov.brRegister
ANVISA's open-data register of notified food products — a market-presence signal, not an evaluation. Absence proves nothing: Route III above lets a lawfully sold product be notified only to a state or municipal authority, never reaching this federal dataset at all.
dados.gov.brKnown gaps
IN 373/2025, IN 418/2025, IN 431/2026 and IN 438/2026 all have retificação windows we have not fully closed — the same silent-amendment risk that moved ANVISA's creatine cap in 2025. IN 418/2025 has not been checked at all. Flagged here rather than asserting a clean bill we have not verified against the gazette.
Health Canada
Monograph sweep monthly; recalls checked daily.
Register
Monographed medicinal ingredients and their permitted routes, direct from the Natural and Non-prescription Health Products Directorate's own compendium. Status and monograph reference are the fields we rely on.
NHPIDRegister
Checked daily, so a recall or advisory against an ingredient you have saved reaches you as an alert rather than waiting for the next monthly monograph sweep.
Recalls & safety alertsFDA · DSHEA
Re-scrubbed monthly.
Register
FDA's list of filed 75-day premarket notifications, with the agency's response letter outcome — used to settle NDI status, never to assert permission.
FDA NDI notificationsRegister
FDA's Generally Recognized As Safe inventory, with the agency's letter of no objection where one was issued.
FDA GRAS inventoryRegister
Ingredients FDA has publicly flagged as adulterants or otherwise unlawful in supplements — the decidable hard-no side of the US surface.
FDA ingredient directoryHow we answer here
The US has no published positive list, so this market runs as decidable gates: we resolve what these registers actually settle — NDI status, pre-DSHEA marketing, known adulterants — and never manufacture a US “permitted” verdict to fill the gap.
SAMR · NHC · GB standards
Loaded from the parsed source instruments; re-verified when a standard is reissued.
Instrument
The Ministry of Health notice listing items usable in health food, and those permitted in ordinary food. Membership decides which rung of the route ladder an ingredient can even reach.
SAMRInstrument
GB 2760 (food additives), GB 14880 (nutrient fortification) and the GB 1903 series for permitted salt and ester forms. A compound form absent from its GB standard reads as not permitted, so these are read as a closed list.
CFSA standards databaseRegister
The raw-material directory that makes the fast filing (备案) route available instead of full registration, with its per-population dose bounds and mandatory label wording.
SAMR filing directoryInstrument
The closed catalogue of health functions a product may lawfully claim, plus the old-to-new wording map from the 2023 reform. A claim outside this catalogue has no route, however well evidenced.
SAMR function catalogueRegister
The CBEC retail-import tariff lines, which govern the channel that avoids domestic registration entirely — and the restrictions attached to each line.
Ministry of FinanceHow we answer here
China returns a position on the SAMR route ladder — registration, filing, cross-border, or no route — never a permissibility verdict. The surface is the exporter's lens: it answers which route is open to you, not whether a product is legal to sell inside the PRC.
Prohibited substances, concentration ceilings and claim tiers — a separate regulatory regime from supplements in every market, and read separately.
AICIS · Poisons Standard
Re-imported each time AICIS publishes an inventory update.
Register
The industrial-chemicals inventory that decides whether a cosmetic ingredient may be introduced at all, read together with IMAP evaluations and SUSMP concentration cut-offs.
AICIS inventory searchEPA
Re-scrubbed monthly.
Instrument
Schedule 4's prohibited list plus Schedules 5–8 for restricted substances, preservatives, colourants and UV filters, consolidated 1 January 2026 — including the PFAS phase-out.
EPA Group StandardFDA · MoCRA · state law
Re-scrubbed monthly.
Instrument
Federal prohibitions and the colour-additive listings, watched section by section against the live eCFR so a rule we cite cannot quietly be repealed underneath us.
eCFR Title 21Instrument
California, Washington, Maryland and others now ban ingredients federal law still allows — so a federally clean formula can be unlawful on the shelf it is actually sold on.
eCFR Title 21How we answer here
FDA does not pre-approve cosmetic ingredients, so this market is federal and state gates only — never a “permitted” verdict.
Every register above is re-read on a schedule, diffed against what we last stored, and an alert raised the moment an authority moves — a dose ceiling, a new prohibition, a repealed instrument. Dated examples of changes MARCO caught are on the markets page.
What this page is not
A provenance map, not legal advice. MARCO is a screening and decision-support tool, and citing a register does not mean that authority endorses us. Where a market publishes no positive list — the US and China on the supplement side, the US on the cosmetic side — MARCO answers only what the registers settle and never invents a permission to fill the gap. For how your own account data is handled, see Trust & Security; for the terms of use, see the disclaimer.
Start free — 4 checks, no card. Every verdict comes cited, or it comes honest.
Team plans & full details on the pricing page.